the aim of this investigation was to design and develop nanoemulsions as novel delivery systems for rapamycin. phase behavior of quaternary systems composed of traicetin (as oil), various surfactants and co-surfactants and water at different surfactant/co-surfactant weight ratios were investigated by the construction of phase diagrams. formulations were taken from the o/w ne region of the phase...

background and objective: free radicals cause many diseases in human and their neutralizing by antioxidants reduces risk of cancers. salvia officinalis from lamiaceae family is one of the valuable plants in traditional medicine. the present study aimed to evaluate the antioxidative and cytotoxic properties of ethanolic extract of the aerial parts of this plant on human prostate and cervical can...

background & aim:cervical cancer is the most common   female genital cancer and the second most common cancer in women in the   world. since the herbal ingredients have been used for centuries to treat   cancer, purpose of the present study was to determine the cytotoxic   effect of hydroalcoholic extract from satureja bachtiarica bungeon   hela cancer cells line. experimental: hela cells line ...

background: ß-carbolines, harmaline and harmine, are the major alkaloids presenting in the seeds of the peganum harmala l. these alkaloids are known as herbal active principals with potential use in pharmaceutical and medicine. objectives: to assess the growth inhibitory effect of phyto-alkaloids, harmaline and harmine, on cancer cell lines. methods: the p. harmala l.’s alkaloids were extracted...

parthenolide is major sesquiterpene lactones present in anthemis haussknechtii boiss. & reut. (feverfew). this compound has many effects on different disease such as migrain and cancer. parthenolide was reported from tanacetum parthenium (l.) sch.bip. but other plants of asteraceae family could contain parthenolide. in this study parthenolide was extracted and identified with two methods, fouri...

background & objective: chlorhexidine solution is one of the widely used mouth antiseptic liquid that prevents teeth tissue damage and also has application as a root canal antiseptic. in this study, cytotoxicity of 2% chlorhexidine solution is compared with another root canal antiseptic, calcium hydroxide powder. materials and methods: cell cytotoxicity of both chemicals was assessed on culture...

objective: biodegradable polycaprolactone/starch composites can be used for bone tissue engineering applications. the effect of the ratio of components on composite properties is of tremendous importance. methods: polycaprolactone/starch composite of 80/20 and 70/30 ratios were fabricated by dissolving them in chloroform followed by evaporation of the solvent. results: the composites were chara...

The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, which measures the reduction of MTT, is commonly used to validate the viability of metabolically active cells. This study was conducted to evaluate and validate the MTT assay to assess the spermatozoal viability of Nili-Ravi buffalo bulls and compare the efficiency of the test with the supravital staining technique (e...

MTT (3-(4,5-dimethyl thiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay is commonly used to validate the viability of metabolically active cells. The study was conducted to examine and validate the MTT test to assess the sperm viability of Nili-Ravi buffalo bulls and compare the efficiency of the test with the supra-vital staining technique (eosin-nigrosine) and hypo-osmotic swelling test. F...